Tuesday, 10th December The 13th International Congress of the Immunology of Diabetes Society 2013

• The prediabetic period – seroconversion and progression as distinct stages with multiple determinants. - Ezio Bonifacio

• HLA-transgenic Mouse Models for Biomarker and Immune Tolerance Investigations - Teresa DiLorenzo
• Immune correlates of disease progression, regulation and therapeutic intervention - Bart Roep
• Chromogranin A and IAPP - Autoantigens for CD4 T Cells - Kathryn Haskins

• Analysis of immune, metabolic and clinical biomarkers implicates inflammatory and stress pathways in the pre-clinical development of type 1 diabetes - Ranjeny Thomas
• Central tolerance against insulin-specific T cells - Mark S Anderson
• Immunodominant antigen targets in T1D: pathophysiological basis and therapeutic opportunities - Roberto Mallone

Lunch with exhibition

• Recessive tolerance to proinsulin in early life is sufficient to prevent autoimmunity in NOD mice. - Gaurang Jhala
• Monoclonal antibody targeting insulin presented in a fixed register modulates type 1 diabetes - Li Zhang
• The role of peripheral antigen in tolerizing insulin-reactive CD8⁺ T cells in Type 1 Diabetes - Terri C Thayer
• Proinflammatory and regulatory autoreactive T cell responses to insulin are dependent upon HLA-DQ genotype - Aaron Michels
• Proinsulin peptide immunotherapy prevents autoimmunity in a humanized model - Vivienne B Gibson

• Beta cell proliferation and islet regeneration induced by endothelial cell-macrophage interactions - Alvin Powers
• The challenge of generating functional beta cells in vitro - Ed Stanley
• Targeting TNF co-stimulation pathways for islet allograft survival - Shane Grey
• Localized intervention in islet transplantation: at the coal face - Andrew Lew

• ITN / JDRF Type 1 Diabetes Preclinical Consortium: a multi-center model for prioritizing treatment strategies in new-onset disease - Ronald G Gill
• Testing Agents For Prevention Or Reversal Of Type 1 Diabetes In Rodents - Lisa M. Spain

Dinner at 3 venues: Maple Tree, Marks & Lorne Hotel

Dessert and dancing at Mantra Lorne from 9:15pm

The conference acknowledges the support of:

CSL

Novo Nordisk

JDRF