Stuart Mannering
A/Prof Stuart Mannering completed his PhD, in 1998, on human Dendritic cells with Prof Derek Hart. After postdocs at The University of Melbourne and the Walter and Eliza Hall Institute, with Len Harision, he established his group at St. Vincent’s Institute of Medical Research in 2008. His group’s research has two related goals. One is to understand ‘how and why’ human T cells cause type 1 diabetes (T1D). The second is to use this knowledge to develop tools and methods for measuring and modulating beta-cell antigen specific T-cell responses in people with T1D. He developed the CFSE-based proliferation assay, identified the first neoepitope implicated in T1D, was the first to isolate and analyze viable human-islet infiltrating T cells and showed the C-peptide is a major autoantigen in human T1D. His recent work has focused on developing clinic friendly assays for measuring beta-cell antigen specific T-cell responses in T1D.
Abstracts this author is presenting:
